A Phase 1 study of BGB-43395 in advanced solid tumors

Study Description

A study to evaluate the safety and effectiveness of the investigational drug BGB-43395, alone or in combination with other therapies, in patients with advanced breast cancer and other solid tumors

Study Details

Registry ID:

NCT06120283

Conditions:

Advanced Solid Tumor, Advanced Breast Cancer, Metastatic Breast Cancer, Hormone-receptor-positive Breast Cancer, Hormone Receptor Positive Breast Carcinoma, Hormone Receptor Positive Malignant Neoplasm of Breast, HER2-negative Breast Cancer, Hormone Receptor Positive HER-2 Negative Breast Cancer, Non-small Cell Lung Cancer

Phase:

Phase 1

Target Enrollment:

399 participants

Start Date:

December 1, 2023

Healthy Volunteers:

No

Study Locations (80 sites)

• Asan Medical Center
  SongpaGu, Seoul TeugbyeolsiSouth Korea, South Korea
• Srinagarind Hospital (Khon Kaen University)
  MuangThailand, Thailand
• Severance Hospital Yonsei University Health System
  SeodaemunGu, Seoul TeugbyeolsiSouth Korea, South Korea
• Seoul National University Bundang Hospital
  BundangGu SeongnamSi, Gyeonggi-doSouth Korea, South Korea
• Gachon University Gil Medical Center
  NamdongGu, Incheon Gwang'yeogsiSouth Korea, South Korea
• Samsung Medical Center
  GangnamGu, Seoul TeugbyeolsiSouth Korea, South Korea
• The Catholic University of Korea, Seoul St Marys Hospital
  SeochoGu, Seoul TeugbyeolsiSouth Korea, South Korea
• Liga Norte Riograndene Contra O Cancer
  NatalBrazil, Brazil
• Instituto Dor de Pesquisa E Ensino Hospital Sao Rafael
  SalvadorBrazil, Brazil
• Institut Paoli Calmettes
  MarseilleFrance, France
• Centre de Lutte Contre Le Cancer Institut Bergonie
  BordeauxFrance, France
• Institut de Cancerologie de Louest
  Saint-HerblainFrance, France
• Institut de Cancerologie de Louest
  St HerblainFrance, France
• Centre Eugene Marquis
  RennesFrance, France
• Fundacao Universidade de Caxias Do Sul Instituto de Pesquisas Em Saude
  PetropolisBrazil, Brazil
• Institut Gustave Roussy
  VillejuifFrance, France
• Instituto Nacional de Cancer
  Rio de JaneiroBrazil, Brazil
• Institut Curie
  ParisFrance, France
• Centre Francois Baclesse
  CaenFrance, France
• Hospital Sirio Libanes Brasilia
  BrasiliaBrazil, Brazil
• Centre Oscar Lambret
  LilleFrance, France
• Icesp Instituto Do Cancer Do Estado de Sao Paulo Octavio Frias de Oliveira
  Sao PauloBrazil, Brazil
• Clinica de Pesquisa E Centro de Estudos Em Oncologia Ginecologica E Mamaria
  Sao PauloBrazil, Brazil
• Hospital Israelita Albert Einstein
  Sao PauloBrazil, Brazil
• Fundacao Pio Xii Hospital de Amor de Barretos
  BarretosBrazil, Brazil
• The Institute of Oncology, Arensia Exploratory Medicine
  ChisinauMoldova, Republic of, Moldova, Republic of
• The Institute of Oncology, Arensia Exploratory Medicine
  ChisinauMoldova, Moldova
• Centro de Pesquisas Oncologicas Cepon
  FlorianopolisBrazil, Brazil
• Hospital Sao Lucas Da Pucrs Uniao Brasileira de Educacao E Assistencia
  Porto AlgreBrazil, Brazil
• Duke Cancer Center
  Durham, North CarolinaUnited States, United States
• James Cancer Hospital and Solove Research Institute
  Columbus, OhioUnited States, United States
• Scri Oncology Partners
  Nashville, TennesseeUnited States, United States
• Washington University School of Medicine
  St Louis, MissouriUnited States, United States
• Washington University School of Medicine
  Saint Louis, MissouriUnited States, United States
• The University of Texas Md Anderson Cancer Center
  Houston, TexasUnited States, United States
• Pulau Pinang Hospital
  GeorgetownMalaysia, Malaysia
• Pulau Pinang Hospital
  George TownMalaysia, Malaysia
• National Cancer Institute (Institut Kanser Negara)
  PutrajayaMalaysia, Malaysia
• University Malaya Medical Centre
  Kuala LumpurMalaysia, Malaysia
• Next Oncology
  Austin, TexasUnited States, United States
• Next Dallas
  Irving, TexasUnited States, United States
• Next Oncology
  San Antonio, TexasUnited States, United States
• Sarawak General Hospital
  KuchingMalaysia, Malaysia
• Sarah Cannon Research Institute (Scri) At Health One
  Denver, ColoradoUnited States, United States
• Sun Yat Sen Memorial Hospital, Sun Yat Sen University (South)
  Guangzhou, GuangdongChina, China
• The First Affiliated Hospital of Nanchang University Branch Donghu
  Nanchang, JiangxiChina, China
• Fujian Cancer Hospital
  Fuzhou, FujianChina, China
• Beijing Cancer Hospital
  Beijing, Beijing MunicipalityChina, China
• Beijing Cancer Hospital
  Beijing, BeijingChina, China
• Fudan University Shanghai Cancer Centerpudong
  Shanghai, ShanghaiChina, China
• Fudan University Shanghai Cancer Centerpudong
  Shanghai, Shanghai MunicipalityChina, China
• Liaoning Cancer Hospital and Institute
  Shenyang, LiaoningChina, China
• Seoul National University Hospital
  Seoul, Seoul TeugbyeolsiSouth Korea, South Korea
• Seoul National University Hospital
  Seoul, Seoul TeugbyeolsiKorea, Republic of, Korea, Republic of
• Seoul National University Bundang Hospital
  Seongnam-si, Gyeonggi-doSouth Korea, South Korea
• Korea University Anam Hospital
  SeongbukGu, Gyeonggi-doSouth Korea, South Korea
• Korea University Anam Hospital
  SeongbukGu, Gyeonggi-doKorea, Republic of, Korea, Republic of
• Seoul National University Bundang Hospital
  BundangGu SeongnamSi, Gyeonggi-doKorea, Republic of, Korea, Republic of
• Severance Hospital Yonsei University Health System
  SeodaemunGu, Seoul TeugbyeolsiKorea, Republic of, Korea, Republic of
• The Catholic University of Korea, Seoul St Marys Hospital
  SeochoGu, Seoul TeugbyeolsiKorea, Republic of, Korea, Republic of
• Samsung Medical Center
  GangnamGu, Seoul TeugbyeolsiKorea, Republic of, Korea, Republic of
• Korea University Anam Hospital
  SeongbukGu, Seoul TeugbyeolsiSouth Korea, South Korea
• Gachon University Gil Medical Center
  NamdongGu, Incheon Gwang'yeogsiKorea, Republic of, Korea, Republic of
• Asan Medical Center
  SongpaGu, Seoul TeugbyeolsiKorea, Republic of, Korea, Republic of
• Harbin Medical University Cancer Hospital
  Harbin, HeilongjiangChina, China
• Nagoya University Hospital
  Nagoya, Aichi-kenJapan, Japan
• Nagoya University Hospital
  Nagoya, AichiJapan, Japan
• Shizuoka Cancer Center
  Suntogun, ShizuokaJapan, Japan
• Genesiscare St Andrews
  Adelaide, South AustraliaAustralia, Australia
• National Cancer Center Hospital East
  Kashiwa, ChibaJapan, Japan
• Townsville University Hospital
  Douglas, QueenslandAustralia, Australia
• Peter Maccallum Cancer Centre
  Melbourne, VictoriaAustralia, Australia
• Austin Health
  Heidelberg, VictoriaAustralia, Australia
• Southern Highlands Private Hospital
  Bowral, New South WalesAustralia, Australia
• Blacktown Cancer and Haematology Centre
  Blacktown, New South WalesAustralia, Australia
• Concord Repatriation General Hospital
  Concord, New South WalesAustralia, Australia
• Macquarie University Hospital
  Macquarie Park, New South WalesAustralia, Australia
• Macquarie University
  North Ryde, New South WalesAustralia, Australia
• Nzcr Christchurch
  ChristchurchNew Zealand, New Zealand
• Harbour Cancer and Wellness
  AucklandNew Zealand, New Zealand

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