A Phase 1/2 study of Imzokitug plus Pumitamig and chemotherapy in advanced Non-Small Cell Lung Cancer

Study Description

A clinical trial testing whether adding a new medicine (Imzokitug) to an existing immunotherapy (Pumitamig) and standard chemotherapy works better and is safe enough for patients newly diagnosed with advanced or metastatic lung cancer that has spread

Study Details

Registry ID:

NCT07680764

Conditions:

Locally Advanced Non-Small Cell Lung Cancer (NSCLC), Metastatic Non-Small Cell Lung Cancer (NSCLC)

Phase:

Phase 2

Target Enrollment:

160 participants

Start Date:

August 31, 2026

Age Range:

18–999 years

Healthy Volunteers:

No

Study Locations (75 sites)

• Local Institution - 0042
  HaileGermany, Germany
• Local Institution - 0003
  Natal/RN, Rio Grande do NorteBrazil, Brazil
• Local Institution - 0020
  MálagaSpain, Spain
• Local Institution - 0162
  Seville, SevilleSpain, Spain
• Local Institution - 0128
  Misterbianco, CataniaItaly, Italy
• Local Institution - 0010
  MajadahondaSpain, Spain
• Local Institution - 0163
  BarcelonaSpain, Spain
• Local Institution - 0068
  BarcelonaSpain, Spain
• Local Institution - 0027
  BarcelonaSpain, Spain
• Local Institution - 0132
  Badalona, BarcelonaSpain, Spain
• Local Institution - 0110
  Marseille, Bouches-du-RhôneFrance, France
• Local Institution - 0087
  Montpellier, Languedoc-RoussillonFrance, France
• Local Institution - 0131
  Nice, Alpes-MaritimesFrance, France
• Local Institution - 0043
  BariItaly, Italy
• Local Institution - 0159
  MilanItaly, Italy
• Local Institution - 0047
  GrenobleFrance, France
• Local Institution - 0014
  RavennaItaly, Italy
• Local Institution - 0011
  Rozzano (MI)Italy, Italy
• Local Institution - 0148
  BergamoItaly, Italy
• Local Institution - 0085
  Saint-HerblainFrance, France
• Local Institution - 0119
  Villejuif, Val-de-MarneFrance, France
• Local Institution - 0109
  ParisFrance, France
• Local Institution - 0019
  Paris, Île-de-France RegionFrance, France
• Local Institution - 0126
  Stuttgart, Baden-WurttembergGermany, Germany
• Local Institution - 0152
  Homburg, SaarlandGermany, Germany
• Local Institution - 0075
  CraiovaRomania, Romania
• Local Institution - 0113
  Timișoara, Timiș CountyRomania, Romania
• Local Institution - 0037
  GuildfordUnited Kingdom, United Kingdom
• Local Institution - 0065
  CologneGermany, Germany
• Local Institution - 0035
  London, Greater LondonUnited Kingdom, United Kingdom
• Local Institution - 0076
  BucharestRomania, Romania
• Local Institution - 0156
  Marburg, HesseGermany, Germany
• Local Institution - 0001
  São PauloBrazil, Brazil
• Local Institution - 0114
  FloreștiRomania, Romania
• Local Institution - 0008
  Cluj-NapocaRomania, Romania
• Local Institution - 0182
  Birmingham, West MidlandsUnited Kingdom, United Kingdom
• Local Institution - 0005
  Barretos, São PauloBrazil, Brazil
• Local Institution - 0125
  HessenGermany, Germany
• Local Institution - 0116
  IașiRomania, Romania
• Local Institution - 0115
  IașiRomania, Romania
• Local Institution - 0006
  Porto Alegre, Rio Grande do SulBrazil, Brazil
• Local Institution - 0094
  Buenos AiresArgentina, Argentina
• Local Institution - 0082
  Rosario, Santa Fe ProvinceArgentina, Argentina
• Local Institution - 0092
  ViedmaArgentina, Argentina
• Local Institution - 0092
  Viedma, Río Negro ProvinceArgentina, Argentina
• Local Institution - 0149
  Santiago, Santiago MetropolitanChile, Chile
• Local Institution - 0081
  Santiago, Santiago MetropolitanChile, Chile
• Local Institution - 0084
  Viña del Mar, ValparaisoChile, Chile
• Local Institution - 0080
  New York, New YorkUnited States, United States
• Local Institution - 0123
  Baltimore, MarylandUnited States, United States
• Local Institution - 0170
  Athens, GeorgiaUnited States, United States
• Local Institution - 0034
  Lexington, KentuckyUnited States, United States
• Local Institution - 0171
  Lexington, KentuckyUnited States, United States
• Local Institution - 0105
  Nashville, TennesseeUnited States, United States
• Local Institution - 0180
  Hattiesburg, MississippiUnited States, United States
• Local Institution - 0135
  Madison, WisconsinUnited States, United States
• Local Institution - 0095
  Houston, TexasUnited States, United States
• Oncology Hematology West PC
  Omaha, NebraskaUnited States, United States
• Local Institution - 0102
  Omaha, NebraskaUnited States, United States
• Nebraska Cancer Specialists
  Grand Island, NebraskaUnited States, United States
• Local Institution - 0144
  Chengdu, SichuanChina, China
• Local Institution - 0050
  Wuhan, HubeiChina, China
• Local Institution - 0048
  Perth, Western AustraliaAustralia, Australia
• Local Institution - 0138
  Fuzhou, FujianChina, China
• Local Institution - 0147
  Nanjing, JiangsuChina, China
• Local Institution - 0038
  Beijing, Beijing MunicipalityChina, China
• Local Institution - 0137
  Hangzhou, ZhejiangChina, China
• Local Institution - 0139
  Hangzhou, ZhejiangChina, China
• Local Institution - 0168
  Hangzhou, ZhejiangChina, China
• Local Institution - 0140
  Shanghai, Shanghai MunicipalityChina, China
• Local Institution - 0169
  Shanghai, Shanghai MunicipalityChina, China
• Local Institution - 0100
  Heidelberg, VictoriaAustralia, Australia
• Local Institution - 0134
  Westmead, New South WalesAustralia, Australia
• Local Institution - 0074
  Gosford, New South WalesAustralia, Australia
• Local Institution - 0167
  Greenslopes, QueenslandAustralia, Australia

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